王利群 博士/教授/硕导

制药与生命科学学院 护理学院 副院长

1、联系方式

常州大学制药与生命科学学院

地址：江苏省常州市常州科教城天润科技大厦A座608邮编：213164

Email：wlq@cczu.edu.cn

2、研究方向

生物催化与生物合成；微生物的选育与应用；基因工程技术与蛋白质的表达

3、近期发表的论文

[1]    The Isoquinoline Alkaloid Dauricine Targets Multiple Molecular Pathways to Ameliorate Alzheimer-Like Pathological Changes In Vitro[J]. Oxidative Medicine and Cellular Longevity, 2018

[2]    The association between caspase-5 gene polymorphisms and rheumatoid arthritis in a Chinese population[J]. Gene, 2018, 642: 307-312

[3]    Identification of key genes related with Alzheimer’s disease treatment through bioinformatics analysis[J]. Journal of Biology and Life Science, 2018, 9 (1):78-90

[4]    Association Between Norepinephrine Transporter Gene rs2242446, rs5569 Polymorphisms and Risk of Major Depressive Disorder. A Meta-analysis[J]. Archives of Medical Research，2018

[5]    一株耐盐菌的分离及其降解特性[J].化工进展，2017，36(03)：1047-1051

[6]    The effect of resveratrol on beta amyloid-induced memory impairment involves inhibition of phosphodiesterase-4 related signaling[J]. Oncotarget, 2016 , 7 (14) :17380-17392

[7]    Biocatalyticsynthesis of ethyl (R)-2-hydroxy-4-phenylbutyrate with a newly solatedRhodotorula mucilaginosa CCZU-G5 in an aqueous/organic biphasic system,Bioresources and Bioprocessing, 2015, 2:6 DOI 10.1186/s40643-015-0037-9

[8]    Engineering Propionibacterium freudenreichii subsp. shermanii for enhanced propionic acid fermentation: Effects of overexpressing propionyl-CoA: Succinate CoAtrans ferase[J]. Metabolic Engineering, 2015, (27): 46-56

[9]    EGFrs11568835 G/A polymorphism is associated with increased risk of rheumatoidarthritis [J]. Biomarkers, 2014, 19: 563-566

[10]The preparation of silk fibroin modified PBT-co-PBS/PEGcomposite films and their effects on clinical human salivary epithelial cellstransplantation [J]. Journal of Biomimetics, Biomaterials &Tissue Engineering Vol. 18 (2013) pp 29-42

4、出版的编著

[1] 李尔炀，蔡志强，王利群等.生物化学[M].北京：化学工业出版社，2010（本人编写9万字）。

[2] 王利群，蔡志强，何玉财等.生物技术[M].南京：东南大学出版社，2010（本人编写7万字）。

5、科研和教研项目

主持和参与完成国家级项目2项，省部级项目近10项，市厅级及横向项目20多项，主持完成教学课题3项，获江苏省科技进步三等奖1项，常州大学“十佳师德标兵”、“优秀基层工作者”等荣誉称号。现主持省级和市级项目各1项。

6、研究生招生专业

生物化工（专业代码：0817Z3）

生物与医药（专业代码：086000）——生物工程方向